Senior Vice President, Strategy and Portfolio Management Job
Job ID 2020-1604
# of Openings 1
Category Research and Development
Type Regular Full-Time
Responsibilities SUMMARY: The SVP, Strategy and Portfolio
Management, will be responsible for providing strategic and
analytic leadership across all areas of R&D pipeline strategy
and management including identifying asset-level, research/early
stage portfolio interactions and implications as well as
highlighting gaps and making recommendations. The VP, Strategy and
Management will provide pipeline and strategic expertise to all
members of the R&D senior leadership team. Additionally, The
SVP, Strategy and Portfolio Management will lead and manage a team
of Program Leaders.
The SVP, Strategy and Portfolio Management, will provide high
level oversight, management and drive across the span of
development from strategy formulation to execution of that
strategy; this encompasses the entire process from preclinical
research through registration.
The Strategy and Portfolio Management team will coordinate
between all internal/external stakeholders (e.g. Clin Ops, Medical,
Pre-clinical, PIs, MSLs, Regulatory, Research, Drug supply,
Publications as well as Investigators, Patient groups) to ensure
alignment, operational efficiency and program success.
Creates and supports a consistent, linked strategic framework
across early and late stage assets to enable strategic
decision-making—including strategic context setting, decision
structuring, risk assessment, value profiles, governance
Provides direction on product development requirements to meet
expectations of external customers and business stakeholders.
Interacts with research and development, marketing, manufacturing,
and regulatory departments and with external stakeholders.
Provides strategic leadership and expertise with respect to
decision making--providing real-time evaluation and identification
of material events, critical analysis of problems and utilization
Monitors pipeline progress and industry benchmarking data,
identifies trends, risks and gaps and recommends specific
strategies to enhance/optimize KPTI’s pipeline. Drives pipeline
review events, processes and deliberations including scenario
planning and trade-off decisions
Partners directly with governance members and senior leaders to
ensure preparation, implementation and follow-up of scientific and
pipeline-related decisions and actions [is this covered in
bullet #2 or can we blend with #2 or bullet below?]
Drives synchronization and harmonization of inputs, outputs and
processes across R&D governance and other pipeline related
forums with a goal of streamlining and enhancing stakeholder
experience associated with the pipeline governance and
evaluation/management process. Specific responsibilities include
chairing of forums, agenda curation and executive
Responsible for project performance, risk management,
administration, financial management and issue resolution for
Qualifications Advanced science degree (such as MD, DO or PhD)
required. MD strongly preferred.
Minimum 15 years of experience in R&D or commercial business
and/or corporate planning in life sciences industry.
Pharmaceutical Industry Acumen – ability to define, develop and
implement business solutions based on trends, opportunities, needs
and market direction within pharmaceutical industry and health care
Willingness to travel domestic and internationally to attend
various meetings or other sites
Familiarity with portfolio assessment and optimization
techniques, with an ability to articulate the pros and cons of
various approaches and demonstrated ability to modify and adapt a
suite of existing or available tools and techniques to fulfil
Deep understanding of the drug development process as well as
Ability to synthesize information from multiple sources,
communicate ideas and data both verbally and written in a
persuasive and appropriate manner in multi-cultural
Analytical Skills – ability to analyze a wide variety of data,
including benchmarking data and financial figures to make strategic
Experience presenting to and interacting with Senior Executives
in R&D and Commercial organizations in Life Sciences.
Ability to articulate and establish processes which impact
Proactive ability to predict issues and problem solve
Ability to drive/influence decision making across all levels of
Proven financial, budget and resource planning experience.
Overview Karyopharm Therapeutics is an innovation driven
pharmaceutical company focused on the discovery, development, and
commercialization of medicines with the goal of improving the lives
of patients with cancer and other major diseases.
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