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Senior Principal Scientist, Genetic Toxicology

Company: Pfizer
Location: Groton
Posted on: June 1, 2021

Job Description:


As a member of the Genetic Toxicology Group within Global Toxicology, this genetic/cellular toxicology expert will evaluate the potential of therapeutics to cause DNA damage. Work will include the development of cellular and molecular biology tools for the purpose of identifying mechanisms of genotoxicity/cellular toxicity. The individual will interface with drug discovery teams to provide genetic toxicology expertise. Specifically, the individual will communicate the interpretation and drug-development implication of results from standard assays and investigational studies. Within Genetic Toxicology, he/she will guide the design of experiments, mentor and develop other scientists and maintain an awareness of current scientific literature. Additionally, the individual will influence the external environment via presentations, publications and membership in consortia. The successful candidate will have strong interpersonal and communication skills required to build networks and partnerships and a strong background in cellular biology.


  • Genetic toxicology subject matter expert
  • Provide genetic toxicology expertise to DSRD and discovery project teams by communicating and interpreting results of standard and investigational genotoxicity studies.
  • Integrate data and present findings and interpretations in written and oral reports to peers, management, and regulatory agencies
  • Explore, develop and apply novel in vitro assay systems to study mechanisms of genotoxicity
  • Guide the design of experiments and mentor other scientist
  • Influence the external environment via presentations, publications and membership in consortia


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  • PhD in cellular biology, molecular biology, molecular toxicology, cancer biology or a related field
  • Demonstrated Genetic Toxicology Subject matter expertise with a minimum of five years of experience
  • Excellent verbal and communication skills
  • Highly organized in terms of independent goal setting and diligence in advancing projects towards goals


  • Experience with error-corrected sequencing and computational biology

Other Job Details:

Last Date to Apply for Job: May 31st, 2021


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

Keywords: Pfizer, Newton , Senior Principal Scientist, Genetic Toxicology, Other , Groton, Massachusetts

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