We are seeking a synthetic organic chemist to join the Process
Chemistry group within Chemical Research and Development (CRD) in
Groton. CRD, as part of Worldwide R&D in Pharmaceutical
Sciences, is responsible for the development of process technology
for the production of active pharmaceutical ingredients (API). CRD
scientists engage in all facets of development from small scale
synthesis in support of Discovery programs, to the development of
the commercial synthetic route. CRD scientists partner with
manufacturing specialists for API synthesis in kilo-lab and pilot
plant facilities, as well as provide support for technology
transfer to Pfizer manufacturing sites and third party
The successful candidate will design, enable and develop
scalable processes to pharmaceutical drug candidates, applying
innovative chemistries, new technologies and statistical
experimental design approaches in a laboratory setting. The ability
to work on and lead multi-disciplinary teams involving chemists,
analysts, engineers, and technologists, and to represent CRD on
cross-functional teams is essential.
- The successful candidate would propose and identify efficient
and robust synthetic routes for the preparation of API's.
- This position requires laboratory experimentation,
participation on API project team and work in collaboration with
scientists from Analytical R&D and other disciplines such as
engineering to further develop synthetic routes into synthetic
- Interpretation of analytical data to drive synthetic
experimental plans and ability to utilize electronic tools (such as
electronic notebook) to document information.
- A desire to continue to develop and apply new skills is
- The successful candidate would also be responsible to
participate in the preparation of technical transfer documents for
manufacture internally or at third parties.
- Compliance on safety and regulatory requirements is expected
and documented through our internal training program.
- The successful candidate would also participate in key
initiatives for CRD and contribute to continuous improvement work
in the department and advancement of the Process Chemistry
discipline through technology, workflow or business impact.
- PhD. in Organic Chemistry (or within 6 months of completing
Ph.D. program). No industrial experience required.
- State of the art knowledge of modern synthetic methodology,
including aspects of asymmetric synthesis, green chemistry,
catalysis and physical organic chemistry as it relates to reaction
mechanism is expected.
- The ability to employ analytical tools, computational and
statistical methodology, and automated laboratory technologies to
enhance process development efficiency is desirable.
- Excellent written and oral communication skills, the ability to
effectively influence the work of others and a general knowledge of
drug development and the pharmaceutical industry are key.
- Laboratory work requiring standing.
- Working at a computer.
- Ability to use sound scientific judgment and analyze data to
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT
- Travel is required on occasion in support of external
manufacture or to participate in scientific conferences.
Please submit a copy of your CV/resume, research summary along
with a cover letter for consideration.
Additional Job Information:
- Eligible for Employee Referral Bonus
- Eligible for Relocation Support
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have questions regarding this matter, please do not hesitate to
contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and
conditions of employment for all employees and job applicants
without regard to race, color, religion, sex, sexual orientation,
age, gender identity or gender expression, national origin,
disability or veteran status. Pfizer also complies with all
applicable national, state and local laws governing
nondiscrimination in employment as well as work authorization and
employment eligibility verification requirements of the Immigration
and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Research and Development